Novel LDA Therapy is now available for your seasonal allergies, food sensitivities and chemical intolerances.

If you have allergies to the environment (trees, dust, grass, etc.), sensitivities to food or chemical intolerances or multiple chemical sensitivities (MCS), our clinic has an effective, novel treatment for you. It’s called Ultra Low Dose Enzyme Activated Immunotherapy or Low Dose Allergen (LDA) Therapy – for short!

This enzyme-activated immunotherapy is used to treat all types of allergies and immune system problems, even autoimmune problems. LDA is delivered in an office visit by intradermal injection into the forearm. LDA therapy begins with treatments every 6-8 weeks for the first 6 treatments. The benefits received from LDA Therapy after the first treatment can be almost immediate for a large majority of patients. Generally speaking, about 60% of patients notice immediate benefits within the first or second injection. However, the maximal benefit for desensitization takes time over the course of the first year with an improved response rate over a series of injections. Most patients will receive 10-15 treatments over the span of 3 years with boosters as needed.

There are 3 ways to Treat and Desensitize patients with Allergies


The conventional medical model has always been a twice weekly to twice monthly allergy shot with your specialist or family doctor. This traditional treatment has been very effective for seasonal or environmental allergens such as pollen or other specific allergens, etc. The downside of conventional injections of course is the frequency of visits required in the first one to two years as well as the treatment being limited to a select number of allergens and may not cover a large range of inhalants when a patient has numerous reactions. In addition, allergy shots are ineffective for patients with autoimmune disease, food sensitivities/allergies and chemical intolerances.


Sublingual Immunotherapy, otherwise called SLIT, has been a favoured alternative oral therapy whereby patients that are tested can have low dose serum prepared by a compounding pharmacy to take twice daily under the tongue in the comfort of your own home. There are no needle pokes and no frequent visits required after initiating therapy. And SLIT can cover a wide range of allergens for desensitization based on your test results. The downside for some patients is trying to remember to take the drops twice daily and continue therapy for 18-24 months on average, for full benefit and desensitization. This therapy is restricted to environmental inhalants and does not cover any foods nor chemicals for desensitization.


Ultra Low Dose Enzyme Activated Immunotherapy is a novel and effective option in the treatment of all forms of allergies. Patients who have used this therapy have found it to be cost effective and enjoy the fact that no further testing is required in order to commence therapy. With less frequent injections, it is time-saving and preferred by many patients, especially those who are wary of needles. It is a very safe therapy, when compared to conventional injections (that can be life-threatening).

How Does LDA work?

LDA is a method of immunotherapy enhanced by a small dose of the enzyme called beta-glucuronidase. The beta-glucuronidase activates extremely low amounts of various allergens (significantly lower than the conventional allergy shots) and stimulates the production of T- suppressor cells.” T-suppressor cells then signal and turn of helper cells that cause misidentification of normal substances in the body the get mislabelled as allergens or foreign invaders. This is where abnormal immune reactions occur, causing intestinal permeability, inflammation, autoimmune conditions and other ailments. Since T- helper cells take some time to mature in the blood stream, the injections for LDA are spaced out every 6-8 weeks initially and then less frequently every few months as treatment progresses. As you can see in the video, an LDA treatment consists of a very shallow injection into the first layer of the skin, in the smallest amount, about 1/20 cc.

LDA includes mixtures of over 300 allergens that allow patients who have multiple food sensitivities or chemical intolerances to respond favourably to treatment. The available LDA mixtures that we carry include:

  • Environmental Inhalants mix: pollens, grasses, dander, dust mites, fungi, yeast, candida species, etc.
  • Food mix: low dose and intermediate dose of over 300 foods
  • Chemical mix: various chemicals perfumes, formaldehyde, etc.
  • Bacterial mixes specific for Autoimmune Conditions

Getting Started

Patients are not required to undergo any allergy testing or screening to begin LDA Therapy. An initial consultation is required so that we can review your full health history, your symptoms and any recent blood work, as these are the most important factors in determining whether or not this therapy is appropriate for you. LDA therapy does require some patient preparation that can be discussed in the initial office visit before beginning LDA desensitization. This preparation includes the review and study of a patient education manual called the Pink Book, by Dr. Shrader, the leading authority and expert on LDA in environmental-related Illness.

LDA Therapy can ease a wide range of conditions including:

  1. Rhinitis, perennial (runny nose, nasal congestion, etc., year `round)
  2. Rhinitis, seasonal, allergic (above but seasonal, hay fever, etc.)
  3. Nasal polyps
  4. Allergic conjunctivitis (itchy/watery eyes)
  5. Asthma, year `round
  6. Repeated chest infections
  7. Chronic sinusitis, documented by X-ray
  8. Chronic face ache/sinus pain, not proven by X-ray or negative X-rays
  9. Secretory otitis media (“glue ear”)
  10. Repeated ear infections
  11. Immediate food allergy (foods cause  itching, swelling, collapse, shock)
  12. Food (or food chemical) allergy or intolerance/adverse response (not  #11 above)
  13. Chemical sensitivity (severe symptoms, when exposed by breathing)
  14. Migraine/severe headaches
  15. Headaches, other
  16. Eczema, “dermatitis”
  17. Contact dermatitis (from skin contact with a substance)
  18. Urticaria (hives)
  19. Swelling of the lips, face or tongue  (angioedema)
  20. Mental confusion (brain “fog,” confusion, etc.)
  21. Hyperactivity, ADD, ADHD, PDD
  22. Epilepsy (any type)
  23. Rheumatoid arthritis (RA)
  24. Osteo-arthritis or joint pains: non-specific
  25. Muscle pains, severe
  26. Ulcerative colitis
  27. Crohn’s disease
  28. “Irritable bowel”, “spastic colon” or chronic diarrhea
  29. Constipation (less than 1 bowel movement on most days)
  30. Gut “fermentation” (bloating after most meals, especially sugar)
  31. Chronic anal irritation/itch (not caused by hemorrhoids)
  32. Chronic vaginal symptoms
  33. Urinary tract symptoms (not due to infection)
  34. Chronic fatigue, not of sudden post-viral onset but of gradual onset
  35. CFIDS, CFS or ME (UK) (History of sudden viral onset, healthy prior
  36. “Candida” or fungal-related illness whose symptoms respond clinically to antifungals
  37. Hyperventilation complex (medical diagnosis, U.K.)
  38. “Environmental Illness (EI)”
  39. Plugged ears, moderately severe
  40. Pruritis
  41. Depression
  42. Insomnia, moderately severe
  43. Vulvadynia
  44. Anosmia
  45. Emotional/Behavior problems (not #21)
  46. Interstitial cystitis (IC), documented
  47. Post nasal drip, chronic, severe
  48. Chronic cough
  49. Asthma, seasonal only
  50. Ankylosing spondylitis, documented
  51. Dermatographia
  52. Autism
  53. Hypertension
  54. Diabetes
  55. Sjogren’s Syndrome
  56. Meniere’s Disease
  57. Psoriasis
  58. Anaphylaxis due to ingested food or food substance
  59. Anaphylaxis, cause unknown (idiopathic)
  60. Tourette’s
  61. Multiple sclerosis **
  62. Rhinitis due to cats only
  63. Pre-menstrual syndrome (PMS)
  64. Conjunctivitis, chronic, diagnosed as “non-allergic”
  65. Raynaud’s
  66. Reactive arthritis (autoimmune, non-RA)
  67. Pharyngitis
  68. Laryngitis
  69. All Autoimmune diseases, especially those associated with one or more HLA receptor

** Only if the patient has significant food or inhalant allergy/sensitivity

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